The Epilepsy study swab pathway is shown below.
Please choose which pathway you would like to take either:
PATHWAY 1 Affected dogs
or
PATHWAY 2 Unaffected dogs
Please also Note: If you sent any previous Epilepsy study swabs to the AHT you will not need to repeat them
Please click on Read More to view the full pathway.
CA TestingThe DNA testing service was approved by Cambridge University last week, and the genetics team can now begin the process of recruiting staff to perform this function. The Italian…
The genetics team from the AHT are settling in at Cambridge and are hoping to get back to normal working very soon.
This will mean recommencing CA testing and also continuing the very important study into “The prevalence if Idiopathic Epilepsy in the Italian Spinone”
?Update from the genetics team at Cambridge?
Our scientists recently tested some more dogs for the genetic variants that we had identified from our genome scan as being potentially associated with IE, but our results suggest that we still do not have quite enough samples to be sure whether or not we can replicate this finding, and we need to be sure of this before we can take the study further. As such we are in great need of samples from dogs affected with IE and those over the age of 7 years with no report of seizure.
The team work very closely with Hannes Lohi’s group on epilepsy in several breeds and so any samples that go to him should be able to be shared with our KC genetics team, and vice versa. All of our AHT samples and the majority of data have travelled with us to Cambridge, so are still available.
Canine lymphoma is a common cancer of the white blood cells [lymphocytes]. It typically presents as swelling of the lymph nodes [glands]. An owner will often first notice a swelling…
The genetics team from the AHT have secured a laboratory at Cambridge University, contracts are still being negotiated between the University of Cambridge the Kennel club and Kennel Club Charitable…
ISCGB Interim CA Breeding Protocol
If you are new to the Spinone or are not familiar with Cerebellar Ataxia (CA), please take the time to learn about this FATAL disease in the Italian Spinone. It occurs when 2 dogs who are carriers of CA are bred together. Statistically 1 in 4 puppies will be affected and have to be euthanased around 9 months of age. A further 2 in 4 puppies will themselves be carriers and can pass this on if bred from, so even in a small litter it is highly likely that 1 or more puppies will be impacted.
As many of you will know the ISCGB has a long relationship with the Animal Health Trust. In 2005 the Canine Genetics Team at the AHT, started working to identify the genetic mutation responsible for the devastating inherited neurological disorder Cerebellar Ataxia (CA) that is known to affect the Italian Spinone.
Championship and Open Show Results for 2021 …… Please email any show results to results@italianspinone.co.uk for inclusion on the website.
Visit our show photo archive at https://www.italianspinone.co.uk/coppermine Here you can see all the pictures for your dog in one place. Click Search and enter all or part of your dogs name excluding affixes, titles etc. For example to see all the pictures for Sh Ch Inostricani Simoni del Michiamo you would enter Simoni in the search box F F F F F F F SHOW PHOTO ARCHIVE.
We may display photos from shows on our Website and Facebook page. If any person does not wish to have their photos displayed please contact the Secretary (privacy@italianspinone.co.uk) and request that they are not displayed.
28.07.2020
The Kennel Club and the Animal Health Trust (AHT) have issued a joint statement today (July 28) to advise that, in the wake of this month’s news of the closure of the AHT, the scientific data and biological material including more than 40,000 DNA samples stored at the Kennel Club Genetics Centre at the AHT’s headquarters in Newmarket have been secured and moved to Cambridge University.
The Kennel Club Charitable Trust has funded the Genetics Centre since 2009. Led by Dr Cathryn Mellersh, the Centre aimed to develop, where possible, simple mouth swab screening tests to determine affected and carrier dogs. In deciding which diseases to investigate, the joint Kennel Club and AHT team was looking at the impact on the health and welfare of dogs, but also on the support of breeders and access to data and samples.